Figure 3 displays the effect of EBV infection on levels of 11 selected genes that encode proteins having a wide range of functions including cell cycle regulation and proliferation (CDKN2A/p16, CCND1, IGFBP3, HSP70, ID2, ID4), DNA repair (BRCA1, TFF1), cell adhesion (ICAM1), immune response (COX2), and angiogenesis (HIF1A) [21,23,27,29-37]. The gene discussed is IGFBP3; the disease is Epstein-Barr virus infection.