The most abundant Cer species in the liver (in descending order) and their level in HF and HFPL mice were (in nmol/liver): Cer 24:1, 24 ± 2 vs 15 ± 1, -36%, P < 0.01; Cer 22:0, 20 ± 2 vs 16 ± 1, -17%, P = 0.23; Cer 24:0, 12 ± 2 vs 11 ± 1, -10%, P = 0.49; Cer 16:0, 10 ± 1 vs 9 ± 1, -13%, P = 0.27. This evidence concerns the gene CBLN1 and hydrops fetalis.