The levels of catalase activity in lung tissue were significantly lower in pulmonary fibrosis compared with controls (p = 0.0010), without any obvious difference between UIP and NSIP (318.8 ± 67.6 nmol/min/mg protein vs. 249.0 ± 29.5; NS) (Figure 1A). The gene discussed is CAT; the disease is idiopathic pulmonary fibrosis.