Anaemia is a qualitative or quantitative deficiency of Hb or red blood cells (RBC) in circulation resulting in a reduced oxygen (O2)-carrying capacity of the blood to organs and tissues.[4] Anaemia in pregnancy is defined as an Hb concentration of < 11 gm/dL or a haematocrit < 0.33 in first and third trimesters, while in the second trimester a fall of 0.5 gm/dL is adjusted for an increase in plasma volume and a value of 10.5 gm/dL is used.[5, 6] However, in India and most of the other developing countries a lower limit of 10 gm/dL is often accepted.[7]. The gene discussed is GSTM1; the disease is anemia (phenotype).