Several different genes have been identified as susceptibility genes of familial PD(FDP)including alpha-synuclein gene (SNCA) and the leucine-rich repeat kinase 2 (LRRK2) mutations, which underlie autosomal dominant forms of PD, and mutations or multiplications of PINK1(PTEN-induced putative kinase 1), PARK7(Protein DJ1), and PARK2(Parkinson juvenile disease protein 2), with autosomal recessive forms of PD [1–4], especially in Chinese [5, 6]. This evidence concerns the gene PRKN and Parkinson disease.