It is known that Sox9 inhibits Wnt signaling in chondrocytes [48] and that abnormal activation of the Wnt pathway in mouse Sertoli cells leads to degeneration of tubules and infertility [49,50], a phenotype reminiscent of the one reported for AMH-Cre Sox9flox/flox mice [18]. The gene discussed is SOX9; the disease is Infertility.