Recent publications reported associations between number of triple CGG nucleotide repeats on the fragile X mental retardation 1 (FMR1) gene and risk towards premature ovarian senescence [1]–[8], leading in milder cases to so-called premature ovarian aging (POA) [2], [9], also called occult primary ovarian insufficiency (OPOI) [10], and at end stage to premature ovarian failure (POF), also called primary ovarian insufficiency (POI) [10]. The gene discussed is FMR1; the disease is premature menopause.