On classifying patients based on HAM (Table 4), the eosinophil counts and the IgE levels (total and A fumigatus specific) were higher in ABPA-CB-HAM compared to both ABPA-S and ABPA-CB, and remained significant even after exclusion of patients with ORF (Table 5). This evidence concerns the gene IGHE and allergic bronchopulmonary aspergillosis.