The 13A cluster contains LMO7 and KCTD12, and the 13B cluster contains MBNL2 and RAP2A. LMO7 interacts with and regulates emerin, a nuclear membrane protein that is defective in X-linked Emery Dreifuss Muscular Dystrophy [10], [32]. The gene discussed is EMD; the disease is Emery-Dreifuss muscular dystrophy.