CES5A and obesity due to melanocortin 4 receptor deficiency: Other module genes related to lipid metabolism and obesity include Anxa5 (annexin A5) [24], Ccna2 (cyclin A2) [25], Ces5 (carboxylesterase 5) [26], Cyp2c38 (cytochrome P450, family 2, subfamily c, polypeptide 38) [27], Setd8 (SET domain containing 8) [28], and Slc16a11 (monocarboxylic acid transporters, member 11) [29].