In this group of MMR-proficient colorectal cancer, only 7 patients had tumors with CD8+/TIA-1- TILs In univariable analysis, survival time differences for patients with CD8+/TIA-1+ TILs were significantly higher compared to patients with absence of CD8+ TILs (p<0.0001). Here, TIA1 is linked to colorectal cancer.