This pro-inflammatory cytokine is capable of causing the release of other pro-inflammatory cytokines, such as IL-8, tumor necrosis factor alpha (TNFα), and GM-CSF, which have been associated with asthma in murine models [9], in humans [10], [11], or with disease severity [12], [13], [14], [15]. The gene discussed is CXCL8; the disease is asthma.