To test our hypothesis we measured serum concentrations of eleven cytokines and chemokines that were recently described to play an important role in asthma pathogenesis: IL-4, IL-5, IL-8, IL-10, IL-12 (p40), IL-13, IL-17, TNFα, GM-CSF, eotaxin, and IFNγ. This evidence concerns the gene IL4 and asthma.