BCL2L11 and plasma cell myeloma: As a proapoptotic protein, downregulation of Bim is more usually associated with cell survival and antiapoptotic signals (Craxton et al, 2005; Morales et al, 2008), whereas increased expression is associated with apoptosis of myeloma cells (Gómez-Benito et al, 2007; Morales et al, 2008).