CSF3 and infection: A meta-analysis (Clark et al, 2005) showed a significant reduction in the length of hospitalisation (hazard ratio: 0.63, 95% CI: 0.49–0.82, P=0.0006) with the use of G-CSF, but only a marginally significant decrease in infection-related mortality (odds ratio: 0.51, 95% CI: 0.26–1.00, P=0.05) and no significant reduction in overall mortality.