On the one hand, the chemokine CXCL9 has been described as a key mediator in homing and metastasis, as confirmed by the fact that expression of CXCL9 and CXCL10 in the lymph nodes facilitates melanoma cell metastasis in a murine model (Kawada et al, 2004). This evidence concerns the gene CXCL9 and melanoma.