In contrast to the Oncotype DX Breast Cancer Assay, where higher expression of cell cycle genes (STK15, MYBL2, MK167 and CCNB1) is associated with increased risk of recurrence [1,2], higher expression of the colon cell cycle genes (such as CDC20, MCM2, MYBL2, CSE1L, MYC and MK167), was found to correlate with a lower risk of recurrence [6]. The gene discussed is MYC; the disease is breast carcinoma.