Another study investigating the significance of preoperative GPS, that includes only serum CRP and serum albumin for postoperative prognostication of patients with colorectal cancer found that upon multivariate analyses using factors such as age, sex, tumor site, serum CEA, CA19-9, CA72-4, CRP, albumin, and GPS revealed that GPS was associated with postoperative mortality [3]. This evidence concerns the gene CRP and colorectal cancer.