In the present study, taking into consideration the morphology, clinical details and in conjunction with IHC with HMWCK and AMACR, 24/40 ASAP (Cat 2A) cases with a negative staining with HMWCK and moderate to strong positive staining with AMACR were finally categorized as prostatic carcinoma of which only 10 were initially (Cat1) reported as carcinoma. This evidence concerns the gene AMACR and carcinoma.