Two cases showing strong positive staining for AMACR and also strongly highlighting the basal cell layer with 34βE12 were diagnosed as HGPIN (Cat 1- one reported as HGPIN and one as NEM), In conjunction with morphology, a negative AMACR stain and a positive basal cell layer with 34βE12, 8 cases were labeled as adenosis (Cat 1 reported as BPH and NEM), 3 as basal cell hyperplasia (Cat 1 reported as BPH) and 3 cases as atrophy one of which being partial atrophy (Cat 1 reported as NEM). The gene discussed is AMACR; the disease is benign prostatic hyperplasia.