ZBTB7A and ovarian carcinoma: To further assess the function of FBI-1 on aggressive behavior of ovarian cancer cells, OVCA 420 (harboring wild-type p53) and SKOV-3 (possessing a single nucleotide deletion at point 267 at codon 90 of p53, which blocks p53 expression [23]) cells were transiently transfected with pEGFP-FBI-1, followed by performing cell migration and invasion assays.