The regional lymph nodes from Ndst1f/fProx-/CreERT2 wildtype littermates showed large areas of CCL21 positive cells that were found to tightly localize to areas of pan-keratin positive tumor metastases (Figure 7C, compare pan-keratin and CCL21 photomicrographs from a representative Cre negative animal, shown above graphs). The gene discussed is CCL21; the disease is neoplasm.