On the other hand, in lymph nodes of Ndst1f/fProx1+/CreERT2 mutants, regional lymph nodes were characterized by not only minimal pan-keratin positive tumor deposits (Figure 7C, left graph); but in contrast to wildtype littermates, the chemokine showed markedly reduced presence/localization of CCL21 with pan-keratin positive tumor areas (Figure 7C, compare representative photomicrographs from Cre positive animal above graphs; and Figure 7D, showing another example at 100× and 400×). Here, CCL21 is linked to neoplasm.