MMP1 and neoplasm: The differences in the mean tumor volume in two groups were statistically significant at 2, 4, and 5 weeks, (p<.04) (control = 349±79; MMP1 = 900±180 mm3 2 wks, control  = 3568±277; MMP1 = 4690±404 mm3 4 wks, and control  = 5636±615; MMP1 = 7891±716 mm3 5 wks respectively).