To elucidate the potential mechanisms underlying the coordinated expression of MEK/ERK pathway-regulated genes in colorectal cancer cells, we screened the predicted promoter regions (1,000 nucleotide sequences upstream of the transcriptional start site of each gene) of all 7,047 informative genes for 559 known transcription factor binding sites assembled in TRANSFAC. This evidence concerns the gene MAP2K7 and colorectal cancer.