MAP2K1 and infection: Our data implies that the plasma level of LT in the early stages of infection was much lower than the MEK1/MAPK suppressive levels under both in vitro and in vivo conditions (Fig. 1B and 1E 1.5 ng/mL LF groups vs. 4A and 4B 50 μg/kg LT groups vs. 4C 48 hrs groups).