To evaluate whether these HAT inhibitor-induced changes in FMR1 mRNA expression are transient or prolonged, we treated lymphoblasts from one FXTAS patient (CGG91 repeats) with 10 μM garcinol for 24 hours, and then removed the garcinol for 48 hours. Here, TMPRSS11D is linked to fragile X-associated tremor/ataxia syndrome.