Infection with Tn:Rv0431 resulted in greater expression of transcripts for IL-12p40, IL-6, Delta4, CD40, GM-CSF, RANTES, TNFα and MCP-1, but not GITRL or iNOS, than WT Mtb, both with (not shown) or without IFNγ costimulation (Figure 5C). This evidence concerns the gene CSF2 and infection.