Furthermore, a total of 18 human immunoreactiveproteins that include the seven known pertussis antigens and newly identifiedantigens (putative ABC transport ATP binding protein, putative ABC transport solutebinding protein, hypothetical proteins BP2818, PBP, EF-Tu, EF-Ts, Ldh, SucC, LivJand SdhA) have been previously found in the Surfaceome or OMV proteome of B.p, indicating that these surface antigens could serve as predominanttargets recognized by the host immune system and, hence, induce strong host immuneresponses. Here, TSFM is linked to pertussis.