Studies have shown that compromised SOD2 activity influences vessel relaxation (Chen et al. 2007), endothelial nitric oxide synthetase expression (Chen et al. 2007), hypertension (Rodríguez-Iturbe et al. 2002), and recovery from ischemia reperfusion (Asimakis et al. 2002). This evidence concerns the gene SOD2 and Hypertension.