CDK1 and malaria: However, the Thr and Tyr residues that are the targets of Wee1 and Myt1 whose phosphorylation inactivates Cdk1 in other eukaryotes are conserved in PfPK5 and other P. falciparum Cdk-related kinases, suggesting the possibility that unidentified functional homologues of these regulators may be present in malaria parasites.