The value of BNP was significantly higher in group B than in group A (Figure 2); the binary logistic regression confirmed that BNP was related to higher prevalence of LVDD (Log-transformation: OR = 2.7, 95%CI = 1.3-5.6, p = 0.006) along with the duration of diabetes (Log-transformation: OR = 1.6, 95%CI = 1.1-2.9, p = 0.046). The gene discussed is NPPB; the disease is diabetes mellitus.