Moreover, BNP was a strong predictor for LVDD in uncontrolled diabetes cohort (AUC = 0.80, 95%CI 0.66-0.89, p < 0.001) with a cut-off value of 25 pg/ml above that the likelihood to show a DD is high (sensitivity = 77% and specificity = 78%) (Figure 3); the rate of patients having BNP > 25 pg/ml was significantly higher in group B (77% vs 22%, p < 0.001). Here, NPPB is linked to diabetes mellitus.