EpCAM is one of the most widely investigated proteins in human cancers, frequently overexpressed in human malignancies, localized on the plasma membrane of tumor cells and albeit at lower levels in the normal epithelia [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17]. The gene discussed is EPCAM; the disease is cancer.