In order to define candidate regions that may harbor specific genes relevant to breast cancer development, we identified the smallest aUPD regions at chromosome 3p21.31 (TUSC4, SEMA3F, SEMA3B, RASSF1, MAPKAPK3, HYAL1, HYAL2, FUS), 3p26.2-p26.1 (LRRN1, SETMAR, SUMF1), 3p26.1 (GRM7), 11q22.3 (CASP, CASP4, CASP5, CASP12, COP1, CARD16, CARD18, GRIA4) (Table 3) in TN breast cancer samples. This evidence concerns the gene CASP4 and breast carcinoma.