As there was a high correlation between two of the pairs of SNPs that were significantly associated with anxiety disorders (rs10521911 and rs6654100 in SMS: r2 = 0.96; and rs6526342 and rs3764885 in SAT1: r2 = 0.86), we randomly dropped one of the SNPs of each pair from the interaction analyses. The gene discussed is SAT1; the disease is anxiety disorder.