PDE3B and infection: We found that infection of INS-1 (832/13) cells with AdPDE3B virus resulted in a ∼10-fold overexpression of PDE3B compared to control Adβ-gal infected cells (Fig. 2A) and that 32P-PDE3B was detected after immunoprecipitation using both PDE3B antibody and an anti-flag M2 affinity gel (Fig. 2B), as well as using mass spectrometry (data not shown).