ANP32A and metastatic malignant neoplasm in the lymph nodes: Table 2 describes the association between low nuclear pp32 levels and more aggressive tumors (higher grade, p = 0.0002, and positive for lymph node metastasis, p = 0.0069, see Table 2). This evidence supports our previous findings, in a separate clinical data set, showing that low pp32 expression correlated with poorly differentiated PDAs [14], [15].