However one recent well-powered study by Elks et al. found a modest association between an obesity risk score comprising alleles from FTO, MC4R, TMEM18, GNPDA2, KCTD15, NEGR1, BDNF and ETV5 (SFRS10) loci and BMI at birth in 7,146 individuals. Here, BDNF is linked to obesity due to melanocortin 4 receptor deficiency.