The difference in suppression of CD4+CD25low and CD4+CD25- was also significantly differed in both RO T1D subjects (−22.2±9.6 vs. 17.8±5.5, respectively, p = 0.0025, n = 11, Figure 6B vs 6A) and in aAb-positive subjects (9.9±8.0 vs. 32.0±8.1%, respectively, p = 0.008, n = 12, Figure 6B vs 6A). This evidence concerns the gene IL2RA and type 1 diabetes mellitus.