The successful clinical use of Exendin-4 and Liraglutide [19] - injectable peptidic GLP-1R agonists and multiple ongoing human trials with other GLP-1 peptidomimetics all support the idea that GLP-1 analogs are probably the most beneficial therapeutic agents for T2DM in today's medical practices [20]. Here, GCG is linked to type 2 diabetes mellitus.