Irregardless the types of prostatitis, with bacterial infection or not, the common feature in most cases is the inflammation of the prostate gland with the presence of white blood cells or elevated levels of cytokines, especially IL-1β and TNF-α, in the expressed prostate secretion (EPS) or post-prostate-message urine [9], [10], [11]. The gene discussed is IL1B; the disease is bacterial infectious disease.