NRG1 and schizophrenia: Mutant mice deficient in NRG1 have been found to exhibit schizophrenia-associated behavioral abnormalities in sensorimotor gating [2], [4], social interactions [5], [9]–[11], latent inhibition [12], and locomotor activity [8], [13], although neurobehavioral features of the individual mutants significantly differ depending upon the targeted isoforms of NRG1 [2], [6], [7]–[13].