As we have not found corresponding data in the literature, we designed the present study with the aim to analyze the relation of subgross appearance of the lesions (unifocal, multifocal, or diffuse distribution of the invasive component) and some phenotypic tumor features, such as ER, PR, and HER2 expression, basal-like phenotype, and histology grade. The gene discussed is ERBB2; the disease is neoplasm.