Corroborating our findings ofγ-H2AX activation, EBV infection induced additional hallmarks of the DDRincluding auto-phosphorylation of the H2AX kinase ATM (pATM Ser1981), andpunctate localization of the damage adaptor 53BP1 (Fig. 1B and 1C). The gene discussed is TP53BP1; the disease is Epstein-Barr virus infection.