PPARG and cancer: Functionally active PPARγ is expressed in a variety of cancer cells, including those from liposarcomas, colon, breast, prostate and liver, which respond to Thiazolidinedione treatment via inducing growth arrest [10-13], However, studies with in vivo cancer models have provided conflicting results, thus questioning the efficacy of PPARγ ligands as chemotherapeutic agents and raising concerns regarding the long-term term use of these as diabetic drugs.