Apoptosis is induced by SSTR3 as a result of the induction of p53 and Bax [35] and is also induced by SSTR2 in HL-60 cells that express endogenous SSTR2 [36] and in human pancreatic cancer cells expressing mutated p53 and devoid of endogenous SSTR2, after correction of the deficiency by expression of SSTR2 [37]. This evidence concerns the gene SSTR2 and familial pancreatic carcinoma.