Hereditary hyperferritinemia cataract syndrome (HHCS), a syndrome of early-onset cataract and hyperferritinemia, is caused by germline mutations in the iron response element (IRE) of the ferritin L-chain (L-ferritin) gene suggesting that the ferritin metabolism plays a crucial role in the pathogenesis of cataract [5-8]. The gene discussed is FTL; the disease is hereditary hyperferritinemia with congenital cataracts.