We observed that the house-keeping gene expression levels were lower in ovarian cancer tissues than in tumor tissues of breast and endometrial cancer patients (GAPDH 24.2 ± 2.6, 22.2 ± 1.2, 22.7 ± 1.4 (SD) Ct; B2 M 22.1 ± 3.4, 18.1 ± 1.5, 17.7 ± 1.9 (SD) Ct; PGK 25.5 ± 2.7, 23.5 ± 1.1, 22.4 ± 3.0 (SD) Ct in the respective tumor patients). This evidence concerns the gene GAPDH and ovarian cancer.