TP53 and neoplasm: 95% CI 1.27-3.02, P = 0.002), larger tumor size (HR 1.72, 95% CI 1.24-2.40, P = 0.001), lymph node involvement (HR 2.61, 95% CI 1.84-3.69, P < 0.001), the presence of distant metastasis at first diagnosis (HR 10.75, 95% CI 6.29-18.37, P < 0.001), p53 overexpression (HR 1.64, 95% CI 1.17-2.31, P = 0.004), and no hormone therapy (HR 1.81, 95% CI 1.21-2.71, P = 0.004) were identified as independent factors that were significantly associated with mortality (Table 3).