We also measured several markers of processes involved in the pathogenesis of preeclampsia, and investigated whether serum cytokine, chemokine and adhesion molecule levels were related to the clinical characteristics and laboratory parameters of the study participants, including markers of overall inflammation (C-reactive protein), endothelial activation (von Willebrand factor antigen) and endothelial injury (fibronectin), oxidative stress (malondialdehyde) and trophoblast debris (cell-free fetal DNA). The gene discussed is FN1; the disease is preeclampsia.