Circulating levels of the pro-inflammatory cytokines IL-6 and TNF-α, the chemokines IL-8, IP-10 and MCP-1, as well as the adhesion molecules ICAM-1 and VCAM-1, were raised in preeclampsia compared with healthy pregnancy, resulting in an overall pro-inflammatory systemic environment. Here, CXCL8 is linked to preeclampsia.