CFTR and listeriosis: Indomethacin, an inhibitor of cyclooxygenase isoenzymes (COX1, COX2) involved in prostaglandin synthesis, thapsigargin, an inhibitor of the endoplasmatic Ca2+ATPase, CFTR II, a selective apical Cl− ion channel inhibitor, and bumetanide, an inhibitor of a basolateral epithelial Na+K+Cl− cotransporter had no significant influence on the number of activated epithelial cells after Listeria infection illustrated as ratio of activated (Cxcl-2+) to infected (GFP+) cells (Fig. S4H).