Sugar or fatty acid metabolisms and PPAR signaling pathways are well known to be T2D-relevant [2], and thus the CNV genes (Uxs1, Ugt2b, and Cyp4a3) in pathways of “starch and sucrose metabolism (00500)”, “pentose and glucuronate interconversions (00040)”, “fatty acid metabolism (00071)”, and “PPAR signaling (03320)” were preferentially selected as well. The gene discussed is UXS1; the disease is type 2 diabetes mellitus.