At day 9 of infection, the majority of Tg cells had divided (CFSEneg, FACS gating showing level of CD44 expression correlating with cell division is shown in Figure S1), and were defined as effector cells (Teff) CD62Llo, IL-7Rα−, CD43+, and CD27−, and CD44int (Figure 1A). Here, SPN is linked to infection.